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Ranked by upvotes, decayed by age, nudged by discussion.
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Synthetic BiologyGene EditingLongevityNeurotechBioinformatics / AIDIYbio & Community LabsBiosecurity & PolicyBiomanufacturingTherapeutics & ClinicLab HardwareFunding & StartupsOther
- 1. ▲ Show BN: A $180 open-source thermocycler that hits 3 °C/s ramp rates (github.com) Show BNLab Hardware 72 points | pipette_punk | | 4 comments
- 2. ▲ Base editor corrects a point mutation in adult mouse liver with no detectable off-targets (biorxiv.org) Gene Editing 63 points | crispr_kid | | 6 comments
- 3. ▲ Ask BN: How do you validate a community lab BSL-1 setup without an institution behind you? Ask BNDIYbio & Community Labs 53 points | helix_witch | | 6 comments
- 4. ▲ A cell-free protein synthesis kit you can freeze-dry at home (protocols.io) Synthetic Biology 49 points | open_assay | | 6 comments
- 5. ▲ The reproducibility crisis is a metadata crisis (nature.com) Bioinformatics / AI 47 points | open_assay | | 6 comments
- 6. ▲ Show BN: I sequenced my sourdough starter and built a strain tracker for it (github.com) Show BNDIYbio & Community Labs 44 points | garage_genome | | 6 comments
- 7. ▲ Precision fermentation hits $2/kg for a single-cell protein at pilot scale (example-biomanufacturing.org) Biomanufacturing 40 points | ferment_or_die | | 6 comments
- 8. ▲ Organoid intelligence: what we can and cannot claim right now (cell.com) Neurotech 38 points | wetware_ann | | 6 comments
- 9. ▲ Screening DNA synthesis orders: the new baseline every provider should meet (example-policy.org) Biosecurity & Policy 32 points | biosafety_bee | | 6 comments
- 10. ▲ Ask BN: Best way to get a plasmid across a border legally? Ask BNBiosecurity & Policy 33 points | plasmid_mule | | 6 comments
- 11. ▲ A public benchmark for protein design models that actually gets wet-lab validated (biorxiv.org) Bioinformatics / AI 36 points | crispr_kid | | 6 comments
- 12. ▲ Mycelium composites pass a commercial fire rating for the first time (example-materials.com) Biomanufacturing 30 points | mycelium_max | | 6 comments
- 13. ▲ Senolytics in humans: reading the phase 2 data honestly (example-longevity-journal.org) Longevity 27 points | open_assay | | 6 comments
- 14. ▲ Ask BN: What killed your first startup — the science or the burn rate? Ask BNFunding & Startups 25 points | ferment_or_die | | 6 comments
- 15. ▲ Structural prediction is solved. Function is not. (example-structural-bio.org) Bioinformatics / AI 24 points | crispr_kid | | 6 comments
- 16. ▲ A ten-line protocol that doubled our transformation efficiency (protocols.io) Synthetic Biology 26 points | helix_witch | | 6 comments
- 17. ▲ Show BN: Open microfluidics — a chip you can cut on a $300 vinyl cutter (github.com) Show BNLab Hardware 29 points | pipette_punk | | 6 comments
- 18. ▲ Community lab network passes 200 spaces worldwide (example-diybio-atlas.org) DIYbio & Community Labs 22 points | helix_witch | | 5 comments
- 19. ▲ Gene therapy pricing is a manufacturing problem, not a science problem (example-therapeutics.org) Therapeutics & Clinic 19 points | wetware_ann | | 6 comments
- 20. ▲ The FDA draft guidance on decentralised manufacturing, annotated (example-regulatory.org) Biosecurity & Policy 17 points | biosafety_bee | | 6 comments
- 21. ▲ Ask BN: Anyone running a lab entirely on second-hand equipment? Ask BNDIYbio & Community Labs 16 points | garage_genome | | 6 comments
- 22. ▲ Cheap continuous culture: a turbidostat from aquarium parts (github.com) Lab Hardware 21 points | garage_genome | | 6 comments
- 23. ▲ Neural organoid recordings released as an open dataset (2.4 TB) (example-datasets.org) Neurotech 11 points | wetware_ann | | 4 comments
- 24. ▲ Longevity clinics are selling interventions with no endpoint (example-longevity-journal.org) Longevity 14 points | biosafety_bee | | 6 comments
- 25. ▲ What a biotech seed round actually looks like in 2026 (example-venture.org) Funding & Startups 10 points | plasmid_mule | | 6 comments
- 26. ▲ Directed evolution in a droplet: 10^7 variants per afternoon (biorxiv.org) Synthetic Biology 16 points | plasmid_mule | | 6 comments
- 27. ▲ Ask BN: Teaching CRISPR to teenagers — what is actually safe? Ask BNDIYbio & Community Labs 9 points | helix_witch | | 6 comments
- 28. ▲ A cheap dye-free viability assay that works in undergrad teaching labs (protocols.io) DIYbio & Community Labs 15 points | open_assay | | 6 comments
- 29. ▲ Show BN: A lab notebook that is just plain text files and a Makefile (github.com) Show BNBioinformatics / AI 20 points | open_assay | | 6 comments
- 30. ▲ A benchtop sequencer teardown, with schematics (example-teardown.org) Lab Hardware 7 points | pipette_punk | | 6 comments
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