LIVE 32 submissions / 186 comments / 1548 upvotes▲72 Show BN: A $180 open-source thermocycler that hits 3 °C/s ramp rates▲63 Base editor corrects a point mutation in adult mouse liver with no detectable off-targets▲53 Ask BN: How do you validate a community lab BSL-1 setup without an institution behind you?▲49 A cell-free protein synthesis kit you can freeze-dry at home▲47 The reproducibility crisis is a metadata crisis▲44 Show BN: I sequenced my sourdough starter and built a strain tracker for it// The revolution will not be peer reviewed.LIVE 32 submissions / 186 comments / 1548 upvotes▲72 Show BN: A $180 open-source thermocycler that hits 3 °C/s ramp rates▲63 Base editor corrects a point mutation in adult mouse liver with no detectable off-targets▲53 Ask BN: How do you validate a community lab BSL-1 setup without an institution behind you?▲49 A cell-free protein synthesis kit you can freeze-dry at home▲47 The reproducibility crisis is a metadata crisis▲44 Show BN: I sequenced my sourdough starter and built a strain tracker for it// The revolution will not be peer reviewed.

biorxiv.org

Everything submitted from this domain.

1. ▲ Base editor corrects a point mutation in adult mouse liver with no detectable off-targets (biorxiv.org) Gene Editing 63 points | crispr_kid | 4 hours ago | 6 comments
2. ▲ A public benchmark for protein design models that actually gets wet-lab validated (biorxiv.org) Bioinformatics / AI 36 points | crispr_kid | 1 day ago | 6 comments
3. ▲ Directed evolution in a droplet: 10^7 variants per afternoon (biorxiv.org) Synthetic Biology 16 points | plasmid_mule | 3 days ago | 6 comments
4. ▲ Cold chain without the cold: trehalose stabilisation for field diagnostics (biorxiv.org) Therapeutics & Clinic 8 points | crispr_kid | 4 days ago | 5 comments