LIVE 32 submissions / 186 comments / 1548 upvotes▲72 Show BN: A $180 open-source thermocycler that hits 3 °C/s ramp rates▲63 Base editor corrects a point mutation in adult mouse liver with no detectable off-targets▲53 Ask BN: How do you validate a community lab BSL-1 setup without an institution behind you?▲49 A cell-free protein synthesis kit you can freeze-dry at home▲47 The reproducibility crisis is a metadata crisis▲44 Show BN: I sequenced my sourdough starter and built a strain tracker for it// The revolution will not be peer reviewed.LIVE 32 submissions / 186 comments / 1548 upvotes▲72 Show BN: A $180 open-source thermocycler that hits 3 °C/s ramp rates▲63 Base editor corrects a point mutation in adult mouse liver with no detectable off-targets▲53 Ask BN: How do you validate a community lab BSL-1 setup without an institution behind you?▲49 A cell-free protein synthesis kit you can freeze-dry at home▲47 The reproducibility crisis is a metadata crisis▲44 Show BN: I sequenced my sourdough starter and built a strain tracker for it// The revolution will not be peer reviewed.

Ask BN

Questions for the movement. Protocol help, career forks, hard problems.

1. ▲ Ask BN: How do you validate a community lab BSL-1 setup without an institution behind you? Ask BN DIYbio & Community Labs 53 points | helix_witch | 7 hours ago | 6 comments
2. ▲ Ask BN: Best way to get a plasmid across a border legally? Ask BN Biosecurity & Policy 33 points | plasmid_mule | 1 day ago | 6 comments
3. ▲ Ask BN: What killed your first startup — the science or the burn rate? Ask BN Funding & Startups 25 points | ferment_or_die | 2 days ago | 6 comments
4. ▲ Ask BN: Anyone running a lab entirely on second-hand equipment? Ask BN DIYbio & Community Labs 16 points | garage_genome | 3 days ago | 6 comments
5. ▲ Ask BN: Teaching CRISPR to teenagers — what is actually safe? Ask BN DIYbio & Community Labs 9 points | helix_witch | 4 days ago | 6 comments