LIVE 32 submissions / 186 comments / 1548 upvotes▲72 Show BN: A $180 open-source thermocycler that hits 3 °C/s ramp rates▲63 Base editor corrects a point mutation in adult mouse liver with no detectable off-targets▲53 Ask BN: How do you validate a community lab BSL-1 setup without an institution behind you?▲49 A cell-free protein synthesis kit you can freeze-dry at home▲47 The reproducibility crisis is a metadata crisis▲44 Show BN: I sequenced my sourdough starter and built a strain tracker for it// The revolution will not be peer reviewed.LIVE 32 submissions / 186 comments / 1548 upvotes▲72 Show BN: A $180 open-source thermocycler that hits 3 °C/s ramp rates▲63 Base editor corrects a point mutation in adult mouse liver with no detectable off-targets▲53 Ask BN: How do you validate a community lab BSL-1 setup without an institution behind you?▲49 A cell-free protein synthesis kit you can freeze-dry at home▲47 The reproducibility crisis is a metadata crisis▲44 Show BN: I sequenced my sourdough starter and built a strain tracker for it// The revolution will not be peer reviewed.

Show BN

Things people built: rigs, organisms, software, spaces.

1. ▲ Show BN: A $180 open-source thermocycler that hits 3 °C/s ramp rates (github.com) Show BN Lab Hardware 72 points | pipette_punk | 3 hours ago | 4 comments
2. ▲ Show BN: I sequenced my sourdough starter and built a strain tracker for it (github.com) Show BN DIYbio & Community Labs 44 points | garage_genome | 20 hours ago | 6 comments
3. ▲ Show BN: Open microfluidics — a chip you can cut on a $300 vinyl cutter (github.com) Show BN Lab Hardware 29 points | pipette_punk | 1 day ago | 6 comments
4. ▲ Show BN: A lab notebook that is just plain text files and a Makefile (github.com) Show BN Bioinformatics / AI 20 points | open_assay | 2 days ago | 6 comments
5. ▲ Show BN: Bioreactor firmware rewritten in Rust, now open source (github.com) Show BN Lab Hardware 13 points | ferment_or_die | 3 days ago | 6 comments