LIVE 32 submissions / 186 comments / 1548 upvotes▲72 Show BN: A $180 open-source thermocycler that hits 3 °C/s ramp rates▲63 Base editor corrects a point mutation in adult mouse liver with no detectable off-targets▲53 Ask BN: How do you validate a community lab BSL-1 setup without an institution behind you?▲49 A cell-free protein synthesis kit you can freeze-dry at home▲47 The reproducibility crisis is a metadata crisis▲44 Show BN: I sequenced my sourdough starter and built a strain tracker for it// The revolution will not be peer reviewed.LIVE 32 submissions / 186 comments / 1548 upvotes▲72 Show BN: A $180 open-source thermocycler that hits 3 °C/s ramp rates▲63 Base editor corrects a point mutation in adult mouse liver with no detectable off-targets▲53 Ask BN: How do you validate a community lab BSL-1 setup without an institution behind you?▲49 A cell-free protein synthesis kit you can freeze-dry at home▲47 The reproducibility crisis is a metadata crisis▲44 Show BN: I sequenced my sourdough starter and built a strain tracker for it// The revolution will not be peer reviewed.

Biosecurity & Policy

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1. ▲ Screening DNA synthesis orders: the new baseline every provider should meet (example-policy.org) Biosecurity & Policy 32 points | biosafety_bee | 1 day ago | 6 comments
2. ▲ Ask BN: Best way to get a plasmid across a border legally? Ask BN Biosecurity & Policy 33 points | plasmid_mule | 1 day ago | 6 comments
3. ▲ The FDA draft guidance on decentralised manufacturing, annotated (example-regulatory.org) Biosecurity & Policy 17 points | biosafety_bee | 3 days ago | 6 comments