Biosafety take: none of this is a problem at BSL-1 with non-pathogenic chassis. The failure mode in community labs is almost never the organism, it is the chemical waste.

Fair. The preprint does have ONT data in supplementary S4, though the coverage is thin.

This is the third time this month someone has posted a "cheap X" build where the cost excludes the thing that actually costs money. Where is the temperature controller in that BOM?

Anyone else notice that the reproducibility argument always ends with "we need better metadata" and never with "we need to fund replication"?

It is in there — line 14, the $22 board. The expensive part historically was the Peltier driver and that is what got cheap.

Strongly agree. Our incident log is 90% solvent handling and 10% sharps. Zero biological.